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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM135A All Species: 23.03
Human Site: S404 Identified Species: 56.3
UniProt: Q9P2D6 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2D6 NP_001099001.1 1515 169840 S404 E L D G D L N S L P I I F E D
Chimpanzee Pan troglodytes XP_001138203 1515 169815 S404 E L D G D L N S L P I I F E D
Rhesus Macaque Macaca mulatta XP_001089896 1308 144316 D224 A L W T Q F L D T V T L H S Q
Dog Lupus familis XP_853259 1517 169912 S404 E L D G D L N S L P I I F E D
Cat Felis silvestris
Mouse Mus musculus Q6NS59 1506 166838 S404 E L D G D L N S L P I I F E D
Rat Rattus norvegicus NP_001128069 1507 167117 S397 P L H G D L N S L P I I F E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510578 1506 167802 S394 E L D G D L N S L P I I F E D
Chicken Gallus gallus XP_419888 1500 166663 C395 L P P L P I E C S E L D G D T
Frog Xenopus laevis Q641I1 1376 154423 L292 L C N Q L Q L L S D P E E I T
Zebra Danio Brachydanio rerio NP_001139066 1338 148314 S254 N L L R A Y Q S L F C Y L T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 35.8 91 N.A. 83.8 81.6 N.A. 76 71.8 39.4 52.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 53.2 95.3 N.A. 91.2 89.4 N.A. 85.1 82.5 56.9 67.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 86.6 N.A. 100 0 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 86.6 N.A. 100 20 6.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 10 0 0 10 0 0 0 0 % C
% Asp: 0 0 50 0 60 0 0 10 0 10 0 10 0 10 60 % D
% Glu: 50 0 0 0 0 0 10 0 0 10 0 10 10 60 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 10 0 0 60 0 0 % F
% Gly: 0 0 0 60 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 60 60 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 20 80 10 10 10 60 20 10 70 0 10 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 10 0 0 0 60 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 10 0 10 0 0 0 0 60 10 0 0 0 0 % P
% Gln: 0 0 0 10 10 10 10 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 70 20 0 0 0 0 10 10 % S
% Thr: 0 0 0 10 0 0 0 0 10 0 10 0 0 10 20 % T
% Val: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _